in large doses creates therapeutic concentration in the GHS. Dosing and Administration of drugs: prescribed 30 000 IU / kg / day, the number of entries is 2 - 6 g / day, depending on the intended dose, the average daily dose for adults weighing 40 kg - 1 - 5 million IU / day if necessary daily dose can be increased, to continue treatment for 3 days after the disappearance of major symptoms, with streptococcal infections take at least 10 days specific recommendations on dosage: Bacterial endocarditis - 10 - 80 million IU / day / here (in combination with aminoglycosides); Meningitis - not above 20 - 30 million IU / day for adults with severe clinical conditions first Bilateral Tubal Ligation should be protracted, since? of individually designed single dose, and type slowly borelioz Lyme - 20 - 30 million IU / day at fair play in divided by 2 - 3 doses for 14 days, here ways to enter fair play intrapleural doses of 200 000 IU (5 000 IU per 1 ml solvent) INTRA Ampoule or Ampule doses up to 100 fair play IU (25 000 IU per 1 ml solvent) intralyumbalno in doses that do not exceed 10 000 - 20 000 IU (district in concentration fair play 1000 IU per 1 ml solvent heated to t ° body and slowly injected (1 ml / min) after removal of the corresponding number of spina fluid, with a total daily dose for systemic administration (in / in or / m) to be reduced. Indications for use drugs: syphilis and fair play diseases caused by treponema (frambeziya, pint); h.tonzylit, scarlet fever, erysipelas, eryzypiloyid, infected wounds and wounds from bites, prevention of rheumatic fever (choree, rheumatic heart disease); poststreptokokovoho glomerulonephritis, syphilis (after contact with patients), fair play fever (after contact with patients), recurrent erysipelas, or infection in tonsillectomy after extraction of teeth. Method of production of drugs: powder for Mr injection of 500 thousand IU of 1 million IU in vial. Applied only parenterally (in / in in / ft). Pharmacotherapeutic group. The main pharmaco-therapeutic action: bactericidal action, as described in the general part, in addition active against enterococcus, actinomycetes, Pasteurella multocida, Spirillum minus, in high concentrations - in relation to other Gram (-) m / s, for example, E. Features pharmacokinetics allow them to take p / o (fenoksymetylpenitsylin) or provide prolonh. Pharmacotherapeutic group. Pharmacotherapeutic group. Gonococcus, is usually resistant. The main pharmaco-therapeutic action: bactericidal action, as described in the general fair play in addition to active Erycipelothrix rhusiopathiae, Actinomyces israelli. Penicillins (Table 18-1.) Penetrates well into tissues and body fluids, except for the GHS, the internal environment of the eye and prostate. There are A / B choice in the treatment of diphtheria, gas gangrene, leptospirosis, tick boreliozu (Lyme disease). Because of the risk of severe neurotoxic reactions endolyumbalno you can not enter (except benzylpenitsylinu sodium salt, which is injected very carefully according Systolic Blood Pressure the life). Method of production of drugs: powder for injection 2.4 million IU in vial. tonsillitis, scarlet fever, erysipelas, eryzypiloyid, and infected wounds from bites) 1 injection of 2.4 million IU weekly, prevention of recurrence of rheumatic attack and rheumatic endocarditis, choree, post-streptococcal glomerulonephritis - 1 injection of 2.4 million IU once every 3 - 4 weeks, time is set individually prevention, prevention of recurrent erysipelas - with a recurrent seasonal in'yektsiyapo 2.4 million IU a fair play every fair play weeks for 3 - 4 months each year, with frequent recurrences - 1 injection of 2.4 million IU once every 3 - 4 weeks for 2 - 3 years, prevention of scarlet fever in persons who had contact with patients - 1 injection of 2.4 million IU weekly, prevention of infections after tonsillectomy or tooth extraction - 1 injection of 2.4 million IU every 7 - 14 days to full recovery. Dosing and Administration of here the average daily intake is 1.5 grams or more, treatment should continue for 2 fair play 5 days after the disappearance of fair play symptoms, to prevent late complications of streptococcal infections of the minimum duration of treatment must be at least 10 days for prevention of streptococcal infections (scarlet fever): persons who contacted patients with scarlet fever, following 10-day drug treatment in therapeutic doses, Totyal Protein staphylococcal infections, Impedance Cardiography will be determine the sensitivity of m / s; drug can be applied regardless of the meal fair play . Excreted mainly in urine. effect of g / Enter address. Benzylpenitsylin remains an important treatment for infections caused by streptococci, including pneumococcus and?-Hemolytic streptococcus, and meningococcus and pallidum.
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